A REVIEW OF GOLD NANOPARTICLES (GNPS) IN THE DEVELOPMENT OF CANCER THERAPY

• M. Punithavathi*, R. Lakshmi, P. Priyadarshini, Summera Rafiq, SK. Jasmine Shahina, Anjum. A

Keywords: Chemo radiotherapy, Gold nanoparticles; Radiation; Drug delivery system;

ABSTRACT:-

Global cancer therapy (GLOBOCAN) estimates that 18 million new instances of cancer are diagnosed each year in the world. The three main types of cancer treatment are chemotherapy, radiation, and surgery. Patients are now being treated with the maximum tolerable dose. One of the primary problems with both radiation and chemotherapy is normal tissue toxicity, so it will be crucial to include the advancement of contemporary nanoparticle-based treatments. While local radiotherapy dose can be increased by directing the GNPs to the tumor, the Gold Nanoparticle (GNP) based systems are very helpful in further improving chemotherapy through controlled releases of chemotherapeutics. In the past two decades, more than 20 therapeutic products based on nanotechnology have been approved for use in clinical trials. The major goal of this review article is to determine how we might expedite the practical application of GNP-based therapeutic systems to decrease typical tissue toxicity while raising the treatment's value. Future cancer treatments will change thanks to nanomedicines in a better way with fewer side effects.